Product Name :
CES2 Peptide Applications :
Blocking Background :
CES1 and CES2 are the two major liver carboxylesterases which belong to the type-B carboxylesterase/lipase family. Helping the body in the detoxification of a wide range of xenobiotics, CES1 and CES2 are involved in the hydrolyzing activation of therapeutic ester and amide pro-drugs, as well as in the detoxification of several narcotic compounds. The catalytic activity of CES1 and CES2 is influenced by both the esterification site and the structure/moiety of the amino acid. While CES1 shows high affinity for aromatic and aliphatic esters, CES2 shows high affinity for 3,6-diacetyl and 6-monoacetly esters, such as those found in morphine and morphine derivatives. Alternative Name :
Cocaine esterase; Carboxylesterase 2; CE-2; hCE-2; Methylumbelliferyl-acetate deacetylase 2; CES-2; ICE Swiss-Prot :
O00748 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide CES2. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5659 CES2 pAb.
CES2 Peptide Applications :
Blocking Background :
CES1 and CES2 are the two major liver carboxylesterases which belong to the type-B carboxylesterase/lipase family. Helping the body in the detoxification of a wide range of xenobiotics, CES1 and CES2 are involved in the hydrolyzing activation of therapeutic ester and amide pro-drugs, as well as in the detoxification of several narcotic compounds. The catalytic activity of CES1 and CES2 is influenced by both the esterification site and the structure/moiety of the amino acid. While CES1 shows high affinity for aromatic and aliphatic esters, CES2 shows high affinity for 3,6-diacetyl and 6-monoacetly esters, such as those found in morphine and morphine derivatives. Alternative Name :
Cocaine esterase; Carboxylesterase 2; CE-2; hCE-2; Methylumbelliferyl-acetate deacetylase 2; CES-2; ICE Swiss-Prot :
O00748 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide CES2. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5659 CES2 pAb.
Blocking peptide available as BS5659PP