COX5A Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
COX5A Peptide Applications :
Blocking Background :
The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. Found in the inner mitochondrial membrane, COX5a, one of two subunits of the COX5 protein, is the heme A-containing chain of the oxidase family that converts one molecule of oxygen and four molecules of hydrogen to two molecules of water. When oxygen levels within the cell are high, transcription of COX5a, the aerobic subunit of the COX5 protein, is up-regulated as the rate of cellular respiration increases. Conversely, when oxygen levels are low, COX5a transcription decreases as the cell works to conserve oxygen by slowing the creation of water. Alternative Name :
Cytochrome c oxidase subunit 5A, mitochondrial; Cytochrome c oxidase polypeptide Va; COX5a; COX-5A Swiss-Prot :
P20674 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide COX5A. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5674 COX5A pAb.
COX5A Peptide Applications :
Blocking Background :
The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. Found in the inner mitochondrial membrane, COX5a, one of two subunits of the COX5 protein, is the heme A-containing chain of the oxidase family that converts one molecule of oxygen and four molecules of hydrogen to two molecules of water. When oxygen levels within the cell are high, transcription of COX5a, the aerobic subunit of the COX5 protein, is up-regulated as the rate of cellular respiration increases. Conversely, when oxygen levels are low, COX5a transcription decreases as the cell works to conserve oxygen by slowing the creation of water. Alternative Name :
Cytochrome c oxidase subunit 5A, mitochondrial; Cytochrome c oxidase polypeptide Va; COX5a; COX-5A Swiss-Prot :
P20674 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide COX5A. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5674 COX5A pAb.
Blocking peptide available as BS5674PP