CYP2E1 Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
CYP2E1 Peptide Applications :
Blocking Background :
Cytochrome P450 2E1 (CYP2E1) localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous levels of substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. CYP2E1 plays an important role in alcohol metabolism and participates in the metabolic activation of various carcinogens. Chronic ethanol consumption results in the induction of hepatic CYP2E1 in humans, which may play an important role in the pathogenesis of alcoholic liver disease. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer. Alternative Name :
Cytochrome P450 2E1; 4-nitrophenol 2-hydroxylase; CYPIIE1; Cytochrome P450-J; Cytochrome P450 2E1, N-terminally processed; CYP2E Swiss-Prot :
P05181 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide CYP2E1. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5686 CYP2E1 pAb.
CYP2E1 Peptide Applications :
Blocking Background :
Cytochrome P450 2E1 (CYP2E1) localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous levels of substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. CYP2E1 plays an important role in alcohol metabolism and participates in the metabolic activation of various carcinogens. Chronic ethanol consumption results in the induction of hepatic CYP2E1 in humans, which may play an important role in the pathogenesis of alcoholic liver disease. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer. Alternative Name :
Cytochrome P450 2E1; 4-nitrophenol 2-hydroxylase; CYPIIE1; Cytochrome P450-J; Cytochrome P450 2E1, N-terminally processed; CYP2E Swiss-Prot :
P05181 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide CYP2E1. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5686 CYP2E1 pAb.
Blocking peptide available as BS5686PP