Product Name :
DNA pol δ 3 Peptide Applications :
Blocking Background :
DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases. In DNA replication, exonucleases are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches. These exonucleases include the family of DNA polymerases, namely DNA pol α, β, δ and ε. DNA pol δ and DNA pol ε are multisubunit enzymes, with DNA pol δ consisting of two subunits which interact with the sliding DNA clamp protein PCNA. DNA pol δ 3, also known as POLD3 or p66, is a 466 amino acid nuclear protein that is required for the proper function of DNA pol δ. Alternative Name :
DNA polymerase delta subunit 3; DNA polymerase delta subunit p66; POLD3; KIAA0039; DNA pol δ3; DNA polδ3; DNApolδ3; DNA pol δ p66; DNA polδ p66 Swiss-Prot :
Q15054 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide DNA pol δ 3. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5699 DNA pol δ 3 pAb.
DNA pol δ 3 Peptide Applications :
Blocking Background :
DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases. In DNA replication, exonucleases are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches. These exonucleases include the family of DNA polymerases, namely DNA pol α, β, δ and ε. DNA pol δ and DNA pol ε are multisubunit enzymes, with DNA pol δ consisting of two subunits which interact with the sliding DNA clamp protein PCNA. DNA pol δ 3, also known as POLD3 or p66, is a 466 amino acid nuclear protein that is required for the proper function of DNA pol δ. Alternative Name :
DNA polymerase delta subunit 3; DNA polymerase delta subunit p66; POLD3; KIAA0039; DNA pol δ3; DNA polδ3; DNApolδ3; DNA pol δ p66; DNA polδ p66 Swiss-Prot :
Q15054 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide DNA pol δ 3. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5699 DNA pol δ 3 pAb.
Blocking peptide available as BS5699PP