Product Name :
EEA1 Peptide Applications :
Blocking Background :
Early endosomes are cytoplasmic compartments that function in receiving and sorting endocytosed proteins for vesicular transport. EEA1 (early endosome antigen 1) is a peripheral membrane protein that co-localizes with the transferrin receptor and Rab5 on early endosomes. EEA1 contains a calmodulin-binding IQ motif and cysteine rich finger motif necessary for its specific localization to the early endosomes. EEA1 has sequence homology to several yeast proteins that have been implicated in membrane trafficking, including Vps27, Fab1 and Vac1. Evidence suggests a possible role for EEA1 in mediating the regulatory effects of 3'-phosphoinositides on membrane trafficking. Alternative Name :
Early endosome antigen 1; Endosome-associated protein p162; Zinc finger FYVE domain-containing protein 2; ZFYVE2 Swiss-Prot :
Q15075 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide EEA1. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5707 EEA1 pAb.
EEA1 Peptide Applications :
Blocking Background :
Early endosomes are cytoplasmic compartments that function in receiving and sorting endocytosed proteins for vesicular transport. EEA1 (early endosome antigen 1) is a peripheral membrane protein that co-localizes with the transferrin receptor and Rab5 on early endosomes. EEA1 contains a calmodulin-binding IQ motif and cysteine rich finger motif necessary for its specific localization to the early endosomes. EEA1 has sequence homology to several yeast proteins that have been implicated in membrane trafficking, including Vps27, Fab1 and Vac1. Evidence suggests a possible role for EEA1 in mediating the regulatory effects of 3'-phosphoinositides on membrane trafficking. Alternative Name :
Early endosome antigen 1; Endosome-associated protein p162; Zinc finger FYVE domain-containing protein 2; ZFYVE2 Swiss-Prot :
Q15075 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide EEA1. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5707 EEA1 pAb.
Blocking peptide available as BS5707PP