FPR1 (I203) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
FPR1 (I203) Peptide Applications :
Blocking Background :
The N-formyl peptide receptor (FPR) is a chemotactic G protein-coupled receptor (GPCR) that is found on the surface of phagocytic leukocytes, such as neutrophils and monocytes. The human FPR family comprises three members, FPR, FPRL1 (also designated lipoxin A4 receptor) and FPRL2, and each family member contains specific residues, which are responsible for determining its ligand specificity. FPR, a seven transmembrane-domain receptor, primarily binds the chemoattractant N-formyl-methionyl-leucyl-phenylalanine (fMLP), which activates several biological processes, including chemotaxis, transcriptional activation, and actin reorganization. FPR also mediates the inhibition of neutrophil migration through binding to specific peptide fragments of annexin I, which causes calcium transients and affects inflammatory responses. Alternative Name :
fMet-Leu-Phe receptor; fMLP receptor; N-formyl peptide receptor; Short name=FPR; N-formylpeptide chemoattractant receptor Swiss-Prot :
P21462 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide FPR1 (I203). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5720 FPR1 (I203) pAb.
FPR1 (I203) Peptide Applications :
Blocking Background :
The N-formyl peptide receptor (FPR) is a chemotactic G protein-coupled receptor (GPCR) that is found on the surface of phagocytic leukocytes, such as neutrophils and monocytes. The human FPR family comprises three members, FPR, FPRL1 (also designated lipoxin A4 receptor) and FPRL2, and each family member contains specific residues, which are responsible for determining its ligand specificity. FPR, a seven transmembrane-domain receptor, primarily binds the chemoattractant N-formyl-methionyl-leucyl-phenylalanine (fMLP), which activates several biological processes, including chemotaxis, transcriptional activation, and actin reorganization. FPR also mediates the inhibition of neutrophil migration through binding to specific peptide fragments of annexin I, which causes calcium transients and affects inflammatory responses. Alternative Name :
fMet-Leu-Phe receptor; fMLP receptor; N-formyl peptide receptor; Short name=FPR; N-formylpeptide chemoattractant receptor Swiss-Prot :
P21462 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide FPR1 (I203). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5720 FPR1 (I203) pAb.
Blocking peptide available as BS5720PP