KIF4A Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
KIF4A Peptide Applications :
Blocking Background :
The kinesin superfamily proteins (KIFs) are microtubule-dependent molecular motors that transport membranous organelles and protein complexes in a microtubule- and ATP-dependent manner. Cells use KIFs to tightly control the direction, destination and speed of transportation of a variety of important functional molecules, including mRNA. KIF4A functions as an essential chromosome-associated molecular motor involved in faithful chromosome segregation. It is found in the nucleoplasm during interphase and on condensed chromosome arms during mitosis. KIF4A accumulates in the mid-zone duing late anaphase and on the cytokinetic ring during cytokinesis. KIF4 binds to and translocates PRC1, a spindle mid-zone-associated cyclin-dependent kinase that plays a role in cytokinesis. KIF4A may also interact with the condensin I and II complexes. Loss of KIF4A leads to chromosome hypercondensation, suggesting that it is necessary for retaining normal chromosome architecture. Alternative Name :
Chromosome-associated kinesin KIF4A; Chromokinesin-A; ChromokinesinA; Chromokinesin A; KIF4 Swiss-Prot :
O95239 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide KIF4A. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5774 KIF4A pAb.
KIF4A Peptide Applications :
Blocking Background :
The kinesin superfamily proteins (KIFs) are microtubule-dependent molecular motors that transport membranous organelles and protein complexes in a microtubule- and ATP-dependent manner. Cells use KIFs to tightly control the direction, destination and speed of transportation of a variety of important functional molecules, including mRNA. KIF4A functions as an essential chromosome-associated molecular motor involved in faithful chromosome segregation. It is found in the nucleoplasm during interphase and on condensed chromosome arms during mitosis. KIF4A accumulates in the mid-zone duing late anaphase and on the cytokinetic ring during cytokinesis. KIF4 binds to and translocates PRC1, a spindle mid-zone-associated cyclin-dependent kinase that plays a role in cytokinesis. KIF4A may also interact with the condensin I and II complexes. Loss of KIF4A leads to chromosome hypercondensation, suggesting that it is necessary for retaining normal chromosome architecture. Alternative Name :
Chromosome-associated kinesin KIF4A; Chromokinesin-A; ChromokinesinA; Chromokinesin A; KIF4 Swiss-Prot :
O95239 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide KIF4A. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5774 KIF4A pAb.
Blocking peptide available as BS5774PP