Product Name :
PCB Peptide Applications :
Blocking Background :
Pyruvate carboxylase (PCB) is a biotinylated mitchondrial enzyme that catalyzes the synthesis of oxaloacetate from pyruvate in a tissue specific manner. In addition to covalently binding the biotin cofactor, PCB contains consensus sequences for the attachment of ATP and the substrate pyruvate. The PCB gene is located on the long arm of chromosome 11. Mutations in PCB metabolism (pyruvate carboxylase deficiency) are known to cause lactic acidosis, hypoglycemia and mental retardation. Alternative Name :
Pyruvate carboxylase, mitochondrial; Pyruvic carboxylase; PCB; PC Swiss-Prot :
P11498 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide PCB. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5841 PCB pAb.
PCB Peptide Applications :
Blocking Background :
Pyruvate carboxylase (PCB) is a biotinylated mitchondrial enzyme that catalyzes the synthesis of oxaloacetate from pyruvate in a tissue specific manner. In addition to covalently binding the biotin cofactor, PCB contains consensus sequences for the attachment of ATP and the substrate pyruvate. The PCB gene is located on the long arm of chromosome 11. Mutations in PCB metabolism (pyruvate carboxylase deficiency) are known to cause lactic acidosis, hypoglycemia and mental retardation. Alternative Name :
Pyruvate carboxylase, mitochondrial; Pyruvic carboxylase; PCB; PC Swiss-Prot :
P11498 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide PCB. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5841 PCB pAb.
Blocking peptide available as BS5841PP