Product Name :
PGRMC2 Peptide Applications :
Blocking Background :
PGRMC2 (progesterone receptor membrane component 2), also known as DG6 (steroid receptor protein DG6) or PMBP (progesterone membrane-binding protein), is a single pass membrane protein belonging to the cytochrome b5 family (MAPR (membrane associated progesterone receptor) subfamily). Expressed in sperm, PGRMC2 is believed to function as a steroid receptor and may participate in the progesterone-dependent sperm acrosome reaction. PGRMC2 shares approximately 50% overall sequence identity with its close relative PGRMC1. The loss of the gene encoding PGRMC2 is associated with metastasis in uterine endocervical adenocarcinomas, implicating a potential role of PGRMC2 in the suppression of metastasis of endocervical adenocarcinomas. Alternative Name :
Membrane-associated progesterone receptor component 2; Progesterone membrane-binding protein; Steroid receptor protein DG6; DG6; PMBP Swiss-Prot :
O15173 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide PGRMC2. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5853 PGRMC2 pAb.
PGRMC2 Peptide Applications :
Blocking Background :
PGRMC2 (progesterone receptor membrane component 2), also known as DG6 (steroid receptor protein DG6) or PMBP (progesterone membrane-binding protein), is a single pass membrane protein belonging to the cytochrome b5 family (MAPR (membrane associated progesterone receptor) subfamily). Expressed in sperm, PGRMC2 is believed to function as a steroid receptor and may participate in the progesterone-dependent sperm acrosome reaction. PGRMC2 shares approximately 50% overall sequence identity with its close relative PGRMC1. The loss of the gene encoding PGRMC2 is associated with metastasis in uterine endocervical adenocarcinomas, implicating a potential role of PGRMC2 in the suppression of metastasis of endocervical adenocarcinomas. Alternative Name :
Membrane-associated progesterone receptor component 2; Progesterone membrane-binding protein; Steroid receptor protein DG6; DG6; PMBP Swiss-Prot :
O15173 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide PGRMC2. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5853 PGRMC2 pAb.
Blocking peptide available as BS5853PP