Product Name :
RGS1 Peptide Applications :
Blocking Background :
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. In mammals, G protein α, β and γ polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their α subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Several Gα GTPase activating proteins (GAPs) have been identified and are designated RGS1, RGS2, RGS4, RGS7, RGS9, RGS10 and GAIP (Gα-interacting protein). Each of these proteins has been shown to deactivate specific Gα isoforms by increasing the rate at which they convert GTP to GDP. RGS2 has been shown to be an inhibitor of Gα q function. RGS9 expression is restricted to photoreceptor cells and RGS9 has been shown to regulate Gα t. Alternative Name :
Regulator of G-protein signaling 1; RGS-1; B-cell activation protein BL34; Early response protein 1R20; 1R20; BL34; IER1 Swiss-Prot :
Q08116 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide RGS1. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5894 RGS1 pAb.
RGS1 Peptide Applications :
Blocking Background :
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. In mammals, G protein α, β and γ polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their α subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Several Gα GTPase activating proteins (GAPs) have been identified and are designated RGS1, RGS2, RGS4, RGS7, RGS9, RGS10 and GAIP (Gα-interacting protein). Each of these proteins has been shown to deactivate specific Gα isoforms by increasing the rate at which they convert GTP to GDP. RGS2 has been shown to be an inhibitor of Gα q function. RGS9 expression is restricted to photoreceptor cells and RGS9 has been shown to regulate Gα t. Alternative Name :
Regulator of G-protein signaling 1; RGS-1; B-cell activation protein BL34; Early response protein 1R20; 1R20; BL34; IER1 Swiss-Prot :
Q08116 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide RGS1. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5894 RGS1 pAb.
Blocking peptide available as BS5894PP