Product Name :
RGS5 Peptide Applications :
Blocking Background :
Regulators of G protein signaling (RGS proteins) are a family of highly diverse, multifunctional signaling proteins that share a conserved 120 amino acid domain (RGS domain). RGS domains bind directly to activated Gα subunits and act as GTPase-activating proteins (GAPs) to attenuate and/or modulate hormone and neurotransmitter receptor-initiated signaling by both Gα-GTP and Gβγ. RGS proteins shorten the lifetime of activated G proteins. Vascular endothelial cells express the RGS protein RGS5, where it correlates with capillary morphogenesis, thus rendering it a candidate gene involved in capillary growth, angiogenesis, and also potentially the pathophysiology of stroke. Alternative Name :
Regulator of G-protein signaling 5; RGS-5 Swiss-Prot :
O15539 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide RGS5. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5897 RGS5 pAb.

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Blocking peptide available as BS5897PP