Product Name :
TFF1 Peptide Applications :
Blocking Background :
Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain. pS2, also designated Md2, BCEI, TFF1 and pNR-2, is a trefoil protein that is highly expressed in normal gastric mucosa. pS2 has also been detected in a number of carcinomas including cancers of the breast, pancreas and stomach. pS2 is not present in normal breast tissue but is inducible by estrogen in MCF7 cells. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. Alternative Name :
Trefoil factor 1; Breast cancer estrogen-inducible protein; PNR-2; PNR2; Polypeptide P1.A; hP1.A; Protein pS2; BCEI; PS2 Swiss-Prot :
P04155 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TFF1. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS60275 TFF1 pAb.
TFF1 Peptide Applications :
Blocking Background :
Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain. pS2, also designated Md2, BCEI, TFF1 and pNR-2, is a trefoil protein that is highly expressed in normal gastric mucosa. pS2 has also been detected in a number of carcinomas including cancers of the breast, pancreas and stomach. pS2 is not present in normal breast tissue but is inducible by estrogen in MCF7 cells. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. Alternative Name :
Trefoil factor 1; Breast cancer estrogen-inducible protein; PNR-2; PNR2; Polypeptide P1.A; hP1.A; Protein pS2; BCEI; PS2 Swiss-Prot :
P04155 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TFF1. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS60275 TFF1 pAb.
Blocking peptide available as BS60275PP