Hexim2 Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Hexim2 Peptide Applications :
Blocking Background :
Hexamethylene bis-acetamide inducible 1 (HEXIM1) and Hexamethylene bisacetamide inducible 2 (HEXIM2) comprise a family of proteins, which inhibit positive transcription elongation factor b (P-TEFb) through association with 7SK. P-TEFb is composed of a catalytic subunit Cdk9 and either Cyclin T1 or T2 as a regulatory subunit. This complex regulates eukaryotic gene expression at the level of elongation. The C-terminal domains of HEXIM proteins interact directly with each other. Via these domains, HEXIM1 and HEXIM2 form stable homo- and hetero-oligomers, which may aid in the formation of the 7SK small nuclear ribonucleic acid particle. Despite their similar functions, HEXIM1 and HEXIM2 exhibit distinct expression patterns in various established cell lines and human tissues. Alternative Name :
Protein HEXIM2; Hexamethylene bis-acetamide-inducible protein 2; ORF Names: L3 Swiss-Prot :
Q96MH2 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Hexim2. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS60281 Hexim2 pAb.
Hexim2 Peptide Applications :
Blocking Background :
Hexamethylene bis-acetamide inducible 1 (HEXIM1) and Hexamethylene bisacetamide inducible 2 (HEXIM2) comprise a family of proteins, which inhibit positive transcription elongation factor b (P-TEFb) through association with 7SK. P-TEFb is composed of a catalytic subunit Cdk9 and either Cyclin T1 or T2 as a regulatory subunit. This complex regulates eukaryotic gene expression at the level of elongation. The C-terminal domains of HEXIM proteins interact directly with each other. Via these domains, HEXIM1 and HEXIM2 form stable homo- and hetero-oligomers, which may aid in the formation of the 7SK small nuclear ribonucleic acid particle. Despite their similar functions, HEXIM1 and HEXIM2 exhibit distinct expression patterns in various established cell lines and human tissues. Alternative Name :
Protein HEXIM2; Hexamethylene bis-acetamide-inducible protein 2; ORF Names: L3 Swiss-Prot :
Q96MH2 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Hexim2. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS60281 Hexim2 pAb.
Blocking peptide available as BS60281PP