CCBE1 Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
CCBE1 Peptide Applications :
Blocking Background :
The gene encoding CCBE1 (Collagen and calcium-binding EGF domain-containing protein 1) is located on chromosome 18 in a region that is frequently found to be deleted in breast and prostate cancers. CCBE1 is a 406 amino acid secreted protein that contains two collagen-like domains and one calcium-binding epidermal growth factor (EGF-like) domain. In general, EGF-like domains include six cysteine residues that are usually involved in disulfide bonds. Calcium-binding EGF-like domains are subject to amino acid substitutions that disrupt their structure or calcium affinity, therefore altering protein function. Downregulation of the gene encoding CCBE1 is observed with high frequency in breast cancer, suggesting that loss of CCBE1 results in changes in cell adhesion and mobility due to its characterization as an extracellular protein. There are three named isoforms of CCBE1 which are produced as a result of alternative splicing events. Alternative Name :
Collagen and calcium-binding EGF domain-containing protein 1; Full of fluid protein homolog; KIAA1983; UNQ1921/PRO4395 Swiss-Prot :
Q6UXH8 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide CCBE1. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS60287 CCBE1 pAb.
CCBE1 Peptide Applications :
Blocking Background :
The gene encoding CCBE1 (Collagen and calcium-binding EGF domain-containing protein 1) is located on chromosome 18 in a region that is frequently found to be deleted in breast and prostate cancers. CCBE1 is a 406 amino acid secreted protein that contains two collagen-like domains and one calcium-binding epidermal growth factor (EGF-like) domain. In general, EGF-like domains include six cysteine residues that are usually involved in disulfide bonds. Calcium-binding EGF-like domains are subject to amino acid substitutions that disrupt their structure or calcium affinity, therefore altering protein function. Downregulation of the gene encoding CCBE1 is observed with high frequency in breast cancer, suggesting that loss of CCBE1 results in changes in cell adhesion and mobility due to its characterization as an extracellular protein. There are three named isoforms of CCBE1 which are produced as a result of alternative splicing events. Alternative Name :
Collagen and calcium-binding EGF domain-containing protein 1; Full of fluid protein homolog; KIAA1983; UNQ1921/PRO4395 Swiss-Prot :
Q6UXH8 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide CCBE1. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS60287 CCBE1 pAb.
Blocking peptide available as BS60287PP