Drosha Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Drosha Peptide Applications :
Blocking Background :
The ribonuclease III superfamily represents a structurally distinct group of double-strand-specific endonucleases with essential roles in RNA maturation, RNA decay, and gene silencing. Initial cleavage of microRNAs is catalysed by Drosha, a nuclease of the RNase III family, which acts on primary miRNA transcripts (pri-miRNAs) in the nucleus. Human Drosha is a component of two multi-protein complexes. The larger complex contains multiple classes of RNA-associated proteins including RNA helicases, proteins that bind double-stranded RNA, novel heterogeneous nuclear ribonucleoproteins and the Ewing's sarcoma family of proteins. The smaller complex is composed of Drosha and the double-stranded-RNA-binding protein, DGCR8. Alternative Name :
Ribonuclease 3; Protein Drosha; Ribonuclease III; RNase III; p241; DROSHA; RN3, RNASE3L; RNASEN Swiss-Prot :
Q9NRR4 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Drosha. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS60422 Drosha pAb.
Drosha Peptide Applications :
Blocking Background :
The ribonuclease III superfamily represents a structurally distinct group of double-strand-specific endonucleases with essential roles in RNA maturation, RNA decay, and gene silencing. Initial cleavage of microRNAs is catalysed by Drosha, a nuclease of the RNase III family, which acts on primary miRNA transcripts (pri-miRNAs) in the nucleus. Human Drosha is a component of two multi-protein complexes. The larger complex contains multiple classes of RNA-associated proteins including RNA helicases, proteins that bind double-stranded RNA, novel heterogeneous nuclear ribonucleoproteins and the Ewing's sarcoma family of proteins. The smaller complex is composed of Drosha and the double-stranded-RNA-binding protein, DGCR8. Alternative Name :
Ribonuclease 3; Protein Drosha; Ribonuclease III; RNase III; p241; DROSHA; RN3, RNASE3L; RNASEN Swiss-Prot :
Q9NRR4 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Drosha. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS60422 Drosha pAb.
Blocking peptide available as BS60422PP