Cleaved-Lamin A (D230+) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Cleaved-Lamin A (D230+) Peptide Applications :
Blocking Background :
Lamins are nuclear membrane structural components that are important in maintaining normal cell functions such as cell cycle control, DNA replication, and chromatin organization. Lamin A/C is cleaved by caspase-6 and serves as a marker for caspase-6 activation. During apoptosis, lamin A/C is specifically cleaved into a large (41-50 kDa) and a small (28 kDa) fragment. The cleavage of lamins results in nuclear disregulation and cell death. Alternative Name :
Prelamin-A/C; Lamin-A/C; Lamin A/C; LaminA/C; 70 kDa lamin; Renal carcinoma antigen NY-REN-32; LMNA; LMN1; Lamin A; LaminA; Lamin-A; Lamin C; LaminC; Lamin-C Swiss-Prot :
P02545 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Cleaved-Lamin A (D230+). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS7014 Cleaved-Lamin A (D230+) pAb.
Cleaved-Lamin A (D230+) Peptide Applications :
Blocking Background :
Lamins are nuclear membrane structural components that are important in maintaining normal cell functions such as cell cycle control, DNA replication, and chromatin organization. Lamin A/C is cleaved by caspase-6 and serves as a marker for caspase-6 activation. During apoptosis, lamin A/C is specifically cleaved into a large (41-50 kDa) and a small (28 kDa) fragment. The cleavage of lamins results in nuclear disregulation and cell death. Alternative Name :
Prelamin-A/C; Lamin-A/C; Lamin A/C; LaminA/C; 70 kDa lamin; Renal carcinoma antigen NY-REN-32; LMNA; LMN1; Lamin A; LaminA; Lamin-A; Lamin C; LaminC; Lamin-C Swiss-Prot :
P02545 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Cleaved-Lamin A (D230+). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS7014 Cleaved-Lamin A (D230+) pAb.
Blocking peptide available as BS7014PP