Cleaved-KLK8 (V33) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Cleaved-KLK8 (V33) Peptide Applications :
Blocking Background :
Kallikreins (KLKs) belong to the serine protease family of proteolytic enzymes. Kallikrein-8 (KLK8), also called neuropsin precursor, ovasin or serine protease 19, is a 260 amino acid secreted protein involved in hippocampal plasticity. Two isoforms exist for this protein. Isoform 1 is the primary form of KLK8 found predominantly in the pancreas. Isoform 2 contains an additional 46 amino acids after amino acid 23 and is predominantly expressed in adult brain and hippocampus. Isoform 2 is not common to the mouse homolog or other primate homologs. In humans, the T to A mutation (c.71-127T>A) leads to the splice variant seen in the human brain. Both isoforms are detected in fetal brain and placenta. In some cancer cells, KLK8 expression can suppress tumor cell invasiveness and lead to a favorable clinical outcome. Alternative Name :
Kallikrein-8; Hk8; Neuropsin; Ovasin; Serine protease 19; Serine protease TADG-14; Tumor-associated differentially expressed gene 14 protein; KLK8; NRPN; PRSS19; TADG14; UNQ283; PRO322; Kallikrein 8; Kallikrein8 Swiss-Prot :
O60259 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Cleaved-KLK8 (V33). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS7042 Cleaved-KLK8 (V33) pAb.
Cleaved-KLK8 (V33) Peptide Applications :
Blocking Background :
Kallikreins (KLKs) belong to the serine protease family of proteolytic enzymes. Kallikrein-8 (KLK8), also called neuropsin precursor, ovasin or serine protease 19, is a 260 amino acid secreted protein involved in hippocampal plasticity. Two isoforms exist for this protein. Isoform 1 is the primary form of KLK8 found predominantly in the pancreas. Isoform 2 contains an additional 46 amino acids after amino acid 23 and is predominantly expressed in adult brain and hippocampus. Isoform 2 is not common to the mouse homolog or other primate homologs. In humans, the T to A mutation (c.71-127T>A) leads to the splice variant seen in the human brain. Both isoforms are detected in fetal brain and placenta. In some cancer cells, KLK8 expression can suppress tumor cell invasiveness and lead to a favorable clinical outcome. Alternative Name :
Kallikrein-8; Hk8; Neuropsin; Ovasin; Serine protease 19; Serine protease TADG-14; Tumor-associated differentially expressed gene 14 protein; KLK8; NRPN; PRSS19; TADG14; UNQ283; PRO322; Kallikrein 8; Kallikrein8 Swiss-Prot :
O60259 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Cleaved-KLK8 (V33). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS7042 Cleaved-KLK8 (V33) pAb.
Blocking peptide available as BS7042PP