HC-II (D68) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
HC-II (D68) Peptide Applications :
Blocking Background :
Heparin cofactor II (HCII) is a glycoprotein in human plasma which rapidly inactivates Thrombin in the presence of dermatan sulfate. Inhibition occurs by formation of a stable equimolar complex between HCII and Thrombin. Certain clinical conditions, such as hepatic failure, disseminated intravascular coagulation, thalasemina and sickle cell anemia, display reduced levels of HCII. However, during pregnancy, physiological levels of HCII expression are elevated. HCII may regulate coagulation and may participate in processes such as inflammation, atherosclerosis and wound repair. HCII is widely distributed among vertebrates and may have a common function in birds, amphibians and mammals. Alternative Name :
HC II; HCF II deficiency; HCF2; Heparin cofactor II precursor; HLS2; Leuserpin 2; LS2; Protease inhibitor leuserpin 2; SERPIND1; Swiss-Prot :
P05546 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide HC-II (D68). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9125 HC-II (D68) pAb.
HC-II (D68) Peptide Applications :
Blocking Background :
Heparin cofactor II (HCII) is a glycoprotein in human plasma which rapidly inactivates Thrombin in the presence of dermatan sulfate. Inhibition occurs by formation of a stable equimolar complex between HCII and Thrombin. Certain clinical conditions, such as hepatic failure, disseminated intravascular coagulation, thalasemina and sickle cell anemia, display reduced levels of HCII. However, during pregnancy, physiological levels of HCII expression are elevated. HCII may regulate coagulation and may participate in processes such as inflammation, atherosclerosis and wound repair. HCII is widely distributed among vertebrates and may have a common function in birds, amphibians and mammals. Alternative Name :
HC II; HCF II deficiency; HCF2; Heparin cofactor II precursor; HLS2; Leuserpin 2; LS2; Protease inhibitor leuserpin 2; SERPIND1; Swiss-Prot :
P05546 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide HC-II (D68). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9125 HC-II (D68) pAb.
Blocking peptide available as BS9125PP