Product Name :
CYP4F2 (M66) Peptide Applications :
Blocking Background :
CYP4F isoforms are involved in the oxidation of important cellular mediators, such as leukotriene B4 (LTB4) and prostaglandins. CYP4F2 catalyzes ω-hydroxylation of LTB4 to a less potent proinflammatory eicosanoid, 20-OH-LTB4, as well as arachidonic acid. CYP4F2 is expressed in liver and kidney. Its expression is repressed by peroxisomal proliferators and induced by retinoic acid. X-linked adrenoleukodystrophy (X-ALD) is a severe neurodegenerative disorder biochemically characterized by elevated levels of very long-chain fatty acids (VLCFA). CYP4F2 participates in the ω-hydroxylation of VLCFAs, which may provide an alternative mode of treatment for X-ALD patients. Alternative Name :
Cyp4f14; CYPIVF1; Cytochrome P450 LTB omega; Cytochrome P450; family 4; subfamily F; polypeptide 2; EC 1.14.14.1; Leukotriene B(4) 20 monooxygenase; Leukotriene B(4) omega hydroxylase; MGC126966; MGC93476; P450 A3; Swiss-Prot :
P78329 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide CYP4F2 (M66). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9135 CYP4F2 (M66) pAb.
CYP4F2 (M66) Peptide Applications :
Blocking Background :
CYP4F isoforms are involved in the oxidation of important cellular mediators, such as leukotriene B4 (LTB4) and prostaglandins. CYP4F2 catalyzes ω-hydroxylation of LTB4 to a less potent proinflammatory eicosanoid, 20-OH-LTB4, as well as arachidonic acid. CYP4F2 is expressed in liver and kidney. Its expression is repressed by peroxisomal proliferators and induced by retinoic acid. X-linked adrenoleukodystrophy (X-ALD) is a severe neurodegenerative disorder biochemically characterized by elevated levels of very long-chain fatty acids (VLCFA). CYP4F2 participates in the ω-hydroxylation of VLCFAs, which may provide an alternative mode of treatment for X-ALD patients. Alternative Name :
Cyp4f14; CYPIVF1; Cytochrome P450 LTB omega; Cytochrome P450; family 4; subfamily F; polypeptide 2; EC 1.14.14.1; Leukotriene B(4) 20 monooxygenase; Leukotriene B(4) omega hydroxylase; MGC126966; MGC93476; P450 A3; Swiss-Prot :
P78329 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide CYP4F2 (M66). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9135 CYP4F2 (M66) pAb.
Blocking peptide available as BS9135PP