KIR2.1 (C122) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
KIR2.1 (C122) Peptide Applications :
Blocking Background :
The KIR2 subunit family includes 2.1, 2.2, 2.3 and 2.4. Unlike G protein-coupled KIR3 subunits, KIR2.1 requires both phosphorylation by PKA and ATP hydrolysis for functional activity. KIR2.1 is expressed in the superior and inferior collicula and the pontine region of the brain, where it moderates synaptic transmission, like many other potassium channels. In the placenta, KIR2.1 is expressed throughout gestation in cytotrophoblast cells. In the kidney, KIR2.1 colocalizes with KIR5.1 in the proximal tubule. KIR2.1, 2.2 and 2.3 associate with the membrane-associated guanylate kinase synapseassociated protein 97 in the cerebellum and heart. Phosphorylation of KIR2.2 by protein kinase A inhibits the associates with SAP97. Alternative Name :
HHBIRK1; HHIRK 1; HHIRK1; HIRK 1; HIRK1; Inward rectifier K; IRK 1; IRK-1; IRK1; IRK2; KCNJ2; KIR2.1; LQT 7; LQT7; Potassium channel; SQT 3; SQT3; Swiss-Prot :
P63252 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide KIR2.1 (C122). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9150 KIR2.1 (C122) pAb.
KIR2.1 (C122) Peptide Applications :
Blocking Background :
The KIR2 subunit family includes 2.1, 2.2, 2.3 and 2.4. Unlike G protein-coupled KIR3 subunits, KIR2.1 requires both phosphorylation by PKA and ATP hydrolysis for functional activity. KIR2.1 is expressed in the superior and inferior collicula and the pontine region of the brain, where it moderates synaptic transmission, like many other potassium channels. In the placenta, KIR2.1 is expressed throughout gestation in cytotrophoblast cells. In the kidney, KIR2.1 colocalizes with KIR5.1 in the proximal tubule. KIR2.1, 2.2 and 2.3 associate with the membrane-associated guanylate kinase synapseassociated protein 97 in the cerebellum and heart. Phosphorylation of KIR2.2 by protein kinase A inhibits the associates with SAP97. Alternative Name :
HHBIRK1; HHIRK 1; HHIRK1; HIRK 1; HIRK1; Inward rectifier K; IRK 1; IRK-1; IRK1; IRK2; KCNJ2; KIR2.1; LQT 7; LQT7; Potassium channel; SQT 3; SQT3; Swiss-Prot :
P63252 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide KIR2.1 (C122). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9150 KIR2.1 (C122) pAb.
Blocking peptide available as BS9150PP