Product Name :
Kv4.1 (N588) Peptide Applications :
Blocking Background :
The KV gene family encodes more than 30 genes that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming α-subunits (KVα), which include the KV1, KV2, KV3 and KV4 proteins, and accessory or KVβ subunits that modify the gating properties of the coexpressed KVα subunits. Differences exist in the patterns of trafficking, biosynthetic processing and surface expression of the major KV1 subunits (KV1.1, KV1.2 and KV1.4) expressed in rat and human brain, suggesting that the individual protein subunits are highly regulated to control for the assembly and formation of functional neuronal channels. Alternative Name :
Potassium voltage-gated channel subfamily D member 1; Voltage-gated potassium channel subunit Kv4.1; KCND1 Swiss-Prot :
Q9NSA2 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Kv4.1 (N588). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9157 Kv4.1 (N588) pAb.
Kv4.1 (N588) Peptide Applications :
Blocking Background :
The KV gene family encodes more than 30 genes that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming α-subunits (KVα), which include the KV1, KV2, KV3 and KV4 proteins, and accessory or KVβ subunits that modify the gating properties of the coexpressed KVα subunits. Differences exist in the patterns of trafficking, biosynthetic processing and surface expression of the major KV1 subunits (KV1.1, KV1.2 and KV1.4) expressed in rat and human brain, suggesting that the individual protein subunits are highly regulated to control for the assembly and formation of functional neuronal channels. Alternative Name :
Potassium voltage-gated channel subfamily D member 1; Voltage-gated potassium channel subunit Kv4.1; KCND1 Swiss-Prot :
Q9NSA2 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Kv4.1 (N588). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9157 Kv4.1 (N588) pAb.
Blocking peptide available as BS9157PP