HUNK (T287) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
HUNK (T287) Peptide Applications :
Blocking Background :
The HUNK (hormonally upregulated Neu-associated kinase) protein, also designated MAK-V in mouse, has been identified as a novel SNF1-related serine/threonine kinase. The human HUNK gene localizes to chromosome 21q22 and encodes a protein with nucleocytoplasmic distribution and localizes to the centrosome. Overexpression of the HUNK protein associates with approximately 50% of breast carcinomas, and may provide diagnostic-prognostic value as a molecular marker. Serine/threonine-protein kinase SNF1-like kinase 2 (SIK) phosphorylates Ser 794 of IRS1 in insulin-stimulated adipocytes, which may modulate the efficiency of insulin signal transduction. SIK is activated by phosphorylation on Thr 175 by STK11 in complex with STE20-related adapter-α and CAB39. Alternative Name :
HUNK; HUNK; MAKV; Swiss-Prot :
P57058 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide HUNK (T287). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9187 HUNK (T287) pAb.
HUNK (T287) Peptide Applications :
Blocking Background :
The HUNK (hormonally upregulated Neu-associated kinase) protein, also designated MAK-V in mouse, has been identified as a novel SNF1-related serine/threonine kinase. The human HUNK gene localizes to chromosome 21q22 and encodes a protein with nucleocytoplasmic distribution and localizes to the centrosome. Overexpression of the HUNK protein associates with approximately 50% of breast carcinomas, and may provide diagnostic-prognostic value as a molecular marker. Serine/threonine-protein kinase SNF1-like kinase 2 (SIK) phosphorylates Ser 794 of IRS1 in insulin-stimulated adipocytes, which may modulate the efficiency of insulin signal transduction. SIK is activated by phosphorylation on Thr 175 by STK11 in complex with STE20-related adapter-α and CAB39. Alternative Name :
HUNK; HUNK; MAKV; Swiss-Prot :
P57058 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide HUNK (T287). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9187 HUNK (T287) pAb.
Blocking peptide available as BS9187PP