MRCKα (L663) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
MRCKα (L663) Peptide Applications :
Blocking Background :
Protein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues. Myotonic dystrophy kinase-related Cdc42-binding (DMPK-like) kinases-a and b (MRCK-a, b) contain a cysteine-rich motif and a putative pleckstrin homology domain. MRCKs can phosphorylate nonmuscle myosin light chain and influences actin-myosin contractility (3,4). MRCK-a can phosphorylate and activate LIM kinases downstream of Cdc42, which leads to inactivation of ADF/cofilin and to Actin cytoskeletal reorganization. MRCK-a can also influence neurite outgrowth promoted by Cdc42 and Rac. Alternative Name :
MRCK alpha; mrck; mrcka; DMPK like; DMPK-like alpha; CDC42 binding protein kinase beta; CDC42-binding protein kinase alpha; CDC42BPA; Swiss-Prot :
Q5VT25 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide MRCKα (L663). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9192 MRCKα (L663) pAb.
MRCKα (L663) Peptide Applications :
Blocking Background :
Protein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues. Myotonic dystrophy kinase-related Cdc42-binding (DMPK-like) kinases-a and b (MRCK-a, b) contain a cysteine-rich motif and a putative pleckstrin homology domain. MRCKs can phosphorylate nonmuscle myosin light chain and influences actin-myosin contractility (3,4). MRCK-a can phosphorylate and activate LIM kinases downstream of Cdc42, which leads to inactivation of ADF/cofilin and to Actin cytoskeletal reorganization. MRCK-a can also influence neurite outgrowth promoted by Cdc42 and Rac. Alternative Name :
MRCK alpha; mrck; mrcka; DMPK like; DMPK-like alpha; CDC42 binding protein kinase beta; CDC42-binding protein kinase alpha; CDC42BPA; Swiss-Prot :
Q5VT25 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide MRCKα (L663). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9192 MRCKα (L663) pAb.
Blocking peptide available as BS9192PP