ERI1 (D298) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
ERI1 (D298) Peptide Applications :
Blocking Background :
Helicase with RNase motif, more commonly designated Dicer, cleaves doublestranded RNA (dsRNA) in the RNA interference and small temporal RNA (stRNA) pathways, producing active small RNA components (siRNAs) which target the destruction of RNA and repress gene expression. Human Dicer cleaves dsRNA independent of ATP. The 3’-5’ exonuclease ERI-1, also known as Protein 3’hExo, degrades Histone mRNA after replication and may be involved in the regulation of RNA interference. ERI-1 has a high affinity for the stem-loop structure of replication-dependent Histone pre-mRNAs. It requires the 5’-ACCCA-3’ sequence present in stem-loop structure. ERI-1 and a stemloop binding protein (SLBP) target opposite faces of a unique highly conserved stem-loop RNA scaffold towards the 3’ end of Histone mRNA. Alternative Name :
3'EXO; THEX1; HEXO; Eri-1 homolog; 3'-5' exoribonuclease 1; Swiss-Prot :
Q8IV48 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide ERI1 (D298). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9202 ERI1 (D298) pAb.
ERI1 (D298) Peptide Applications :
Blocking Background :
Helicase with RNase motif, more commonly designated Dicer, cleaves doublestranded RNA (dsRNA) in the RNA interference and small temporal RNA (stRNA) pathways, producing active small RNA components (siRNAs) which target the destruction of RNA and repress gene expression. Human Dicer cleaves dsRNA independent of ATP. The 3’-5’ exonuclease ERI-1, also known as Protein 3’hExo, degrades Histone mRNA after replication and may be involved in the regulation of RNA interference. ERI-1 has a high affinity for the stem-loop structure of replication-dependent Histone pre-mRNAs. It requires the 5’-ACCCA-3’ sequence present in stem-loop structure. ERI-1 and a stemloop binding protein (SLBP) target opposite faces of a unique highly conserved stem-loop RNA scaffold towards the 3’ end of Histone mRNA. Alternative Name :
3'EXO; THEX1; HEXO; Eri-1 homolog; 3'-5' exoribonuclease 1; Swiss-Prot :
Q8IV48 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide ERI1 (D298). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9202 ERI1 (D298) pAb.
Blocking peptide available as BS9202PP