CD32-C (D286) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
CD32-C (D286) Peptide Applications :
Blocking Background :
CD32 (also designated FcγRII) is a low affinity receptor for the Fc fragment of aggregated IgG. CD32 is responsible for the clearance of immunocomplexes by macrophages and also plays an important role in the regulation of , production by B cells. IgG can noncooperatively bind either one or two highly glycosylated CD32 molecules, and this binding delivers a negative signal for B cells. CD32 exists as several isoforms that are produced by alternative splicing of three distinct genes, A, B and C. These isoforms are designated FcγRIIA, FcγRIIB1, FcγRIIB3 and FcγRIIC. All isoforms are present on monocytes, placental trophoblasts and endothelial cells. In addition, the FcγRIIB forms are present on B lymphocytes, and the FcγRIIA and FcγRIIC forms are found on neutrophils. Alternative Name :
CD32C; CDw32; Fc fragment of IgG low affinity IIc receptor; Fc gamma RII c; Fc gamma RIIc; Fc-gamma RII-c; Fc-GAMMA-RIIC; FCGR2C; FcRII c; IgG Fc receptor II c; Ly-17; Ly-m20; LyM-1; Lymphocyte antigen 17; MGC23887; MGC30032; Swiss-Prot :
P31995 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide CD32-C (D286). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9204 CD32-C (D286) pAb.
CD32-C (D286) Peptide Applications :
Blocking Background :
CD32 (also designated FcγRII) is a low affinity receptor for the Fc fragment of aggregated IgG. CD32 is responsible for the clearance of immunocomplexes by macrophages and also plays an important role in the regulation of , production by B cells. IgG can noncooperatively bind either one or two highly glycosylated CD32 molecules, and this binding delivers a negative signal for B cells. CD32 exists as several isoforms that are produced by alternative splicing of three distinct genes, A, B and C. These isoforms are designated FcγRIIA, FcγRIIB1, FcγRIIB3 and FcγRIIC. All isoforms are present on monocytes, placental trophoblasts and endothelial cells. In addition, the FcγRIIB forms are present on B lymphocytes, and the FcγRIIA and FcγRIIC forms are found on neutrophils. Alternative Name :
CD32C; CDw32; Fc fragment of IgG low affinity IIc receptor; Fc gamma RII c; Fc gamma RIIc; Fc-gamma RII-c; Fc-GAMMA-RIIC; FCGR2C; FcRII c; IgG Fc receptor II c; Ly-17; Ly-m20; LyM-1; Lymphocyte antigen 17; MGC23887; MGC30032; Swiss-Prot :
P31995 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide CD32-C (D286). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9204 CD32-C (D286) pAb.
Blocking peptide available as BS9204PP