CD272 (W153) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
CD272 (W153) Peptide Applications :
Blocking Background :
B and T lymphocyte attenuator (BTLA,CD272) is an immunoglobulin domain-containing glycoprotein whose expression is induced during T cell activation. BTLA is similar to CTLA-4 and PD-1, all of which are co-inhibitory receptors belonging to the CD28 family. However, unlike CTLA-4 and PD-1, BTLA does not interact with B7-Ig family counter receptors. Rather, the herpesvirus entry mediator (HVEM), a TNF receptor, acts as a molecular switch that modulates T cell activation by propagating inhibitory signals through BTLA. The BTLA-HVEM interaction is conserved between mouse and human, suggesting that this system is an important pathway regulating lymphocyte activation. Alternative Name :
BTLA; BTLA; BTLA1; CD272; CD272 antigen; FLJ16065; MGC129743; Swiss-Prot :
Q7Z6A9 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide CD272 (W153). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9212 CD272 (W153) pAb.
CD272 (W153) Peptide Applications :
Blocking Background :
B and T lymphocyte attenuator (BTLA,CD272) is an immunoglobulin domain-containing glycoprotein whose expression is induced during T cell activation. BTLA is similar to CTLA-4 and PD-1, all of which are co-inhibitory receptors belonging to the CD28 family. However, unlike CTLA-4 and PD-1, BTLA does not interact with B7-Ig family counter receptors. Rather, the herpesvirus entry mediator (HVEM), a TNF receptor, acts as a molecular switch that modulates T cell activation by propagating inhibitory signals through BTLA. The BTLA-HVEM interaction is conserved between mouse and human, suggesting that this system is an important pathway regulating lymphocyte activation. Alternative Name :
BTLA; BTLA; BTLA1; CD272; CD272 antigen; FLJ16065; MGC129743; Swiss-Prot :
Q7Z6A9 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide CD272 (W153). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9212 CD272 (W153) pAb.
Blocking peptide available as BS9212PP