p53R2 (F156) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
p53R2 (F156) Peptide Applications :
Blocking Background :
p53 is a transcription factor that mediates cell cycle arrest and apoptosis by binding to DNA and activating the transcription of specific genes. p53 is also thought to be involved in DNA repair by the transcriptional activation of a ribonucleotide reductase gene, p53R2, after exposure to genotoxic stresses. p53R2 displays a significant similarity to ribonucleotide reductase small subunit (R2), and the expression of R2 is elevated at the onset of the S-phase of the cell cycle. However, only p53R2 expression is induced in response to ultraviolet and g-irradiation and adriamycin treatment. p53R2 translocates to the nucleus upon DNA damage, and subsequently, supplies an immediate pool of dNTPs necessary for DNA repair. Alternative Name :
RRM 2B; RRM2B; p53R2; p53 R2; MGC42116; MTDPS8A; MTDPS8B; Swiss-Prot :
Q7LG56 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p53R2 (F156). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9220 p53R2 (F156) pAb.
p53R2 (F156) Peptide Applications :
Blocking Background :
p53 is a transcription factor that mediates cell cycle arrest and apoptosis by binding to DNA and activating the transcription of specific genes. p53 is also thought to be involved in DNA repair by the transcriptional activation of a ribonucleotide reductase gene, p53R2, after exposure to genotoxic stresses. p53R2 displays a significant similarity to ribonucleotide reductase small subunit (R2), and the expression of R2 is elevated at the onset of the S-phase of the cell cycle. However, only p53R2 expression is induced in response to ultraviolet and g-irradiation and adriamycin treatment. p53R2 translocates to the nucleus upon DNA damage, and subsequently, supplies an immediate pool of dNTPs necessary for DNA repair. Alternative Name :
RRM 2B; RRM2B; p53R2; p53 R2; MGC42116; MTDPS8A; MTDPS8B; Swiss-Prot :
Q7LG56 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p53R2 (F156). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9220 p53R2 (F156) pAb.
Blocking peptide available as BS9220PP