Product Name :
Fibrinogen β (T417) Peptide Applications :
Blocking Background :
Fibrinogen is important in platelet aggregation, the final step of the coagulation cascade (i.e., the formation of Fibrin) and determination of plasma viscosity and erythrocyte aggregation. It is both constitutively expressed and inducible during an acute phase reaction. Hemostasis following tissue injury deploys essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Following vascular injury, Fibrinogen is cleaved by Thrombin to form Fibrin, which is the most abundant component of blood clots. The cleavage products of Fibrinogen regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Alternative Name :
Fibrinogen beta chain; Fibrinopeptide B; Fibrinogen beta chain; FGB; Fibrinogen β; Fibrinogenβ; Fibrinogen-β Swiss-Prot :
P02675 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Fibrinogen β (T417). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9222 Fibrinogen β (T417) pAb.
Fibrinogen β (T417) Peptide Applications :
Blocking Background :
Fibrinogen is important in platelet aggregation, the final step of the coagulation cascade (i.e., the formation of Fibrin) and determination of plasma viscosity and erythrocyte aggregation. It is both constitutively expressed and inducible during an acute phase reaction. Hemostasis following tissue injury deploys essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Following vascular injury, Fibrinogen is cleaved by Thrombin to form Fibrin, which is the most abundant component of blood clots. The cleavage products of Fibrinogen regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Alternative Name :
Fibrinogen beta chain; Fibrinopeptide B; Fibrinogen beta chain; FGB; Fibrinogen β; Fibrinogenβ; Fibrinogen-β Swiss-Prot :
P02675 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Fibrinogen β (T417). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9222 Fibrinogen β (T417) pAb.
Blocking peptide available as BS9222PP