Tollip (W151) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Tollip (W151) Peptide Applications :
Blocking Background :
Tollip (toll-interacting protein) serves as a suppressor of innate immunity signaling and links the serine/threonine kinase IRAK to the IL-1 receptor complex upon receptor activation. Overexpression of Tollip in HEK-293 cells inhibits NFκB activation in response to TLR2 and TLR4 signaling. Negative regulation of TLR signaling by Tollip may limit the production of proinflammatory mediators during inflammation and infection. Tollip forms a complex with Tom1 to regulate endosomal trafficking of ubiquitinated proteins. The Tollip protein shows ubiquitous expression in mouse. Alternative Name :
Adapter protein; FLJ33531; IL 1RAcPIP; IL1RAcPIP; TOLIP; TOLIP; Toll interacting protein; Toll-interacting protein; tollip Swiss-Prot :
Q9H0E2 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Tollip (W151). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9228 Tollip (W151) pAb.
Tollip (W151) Peptide Applications :
Blocking Background :
Tollip (toll-interacting protein) serves as a suppressor of innate immunity signaling and links the serine/threonine kinase IRAK to the IL-1 receptor complex upon receptor activation. Overexpression of Tollip in HEK-293 cells inhibits NFκB activation in response to TLR2 and TLR4 signaling. Negative regulation of TLR signaling by Tollip may limit the production of proinflammatory mediators during inflammation and infection. Tollip forms a complex with Tom1 to regulate endosomal trafficking of ubiquitinated proteins. The Tollip protein shows ubiquitous expression in mouse. Alternative Name :
Adapter protein; FLJ33531; IL 1RAcPIP; IL1RAcPIP; TOLIP; TOLIP; Toll interacting protein; Toll-interacting protein; tollip Swiss-Prot :
Q9H0E2 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Tollip (W151). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9228 Tollip (W151) pAb.
Blocking peptide available as BS9228PP