CD1e (D248) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
CD1e (D248) Peptide Applications :
Blocking Background :
CD1E, also known as R2 or CD1A, is a 322 amino acid single-pass type I membrane protein that localizes to the lumen of the endoplasmic reticulum, as well as to the golgi apparatus, and contains one Ig-like domain. Expressed in a variety of tissues and on cortical thymocytes, dendritic cells and Langerhans cells, CD1E exists as a heterodimer with beta-2-Microglobulin and is necessary for the presentation of glycolipid antigens on the cell surface. CD1E is subject to post-translational mono-ubiquitination and may also be proteolytically cleaved in endosomes to yield a soluble protein. CD1E is present on the surface of some T-cell leukemias, suggesting a possible role in tumorigenesis. Alternative Name :
CD1A; CD1e antigen; CD1E antigen; e polypeptide; CD1e molecule; Swiss-Prot :
P15812 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide CD1e (D248). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9241 CD1e (D248) pAb.
CD1e (D248) Peptide Applications :
Blocking Background :
CD1E, also known as R2 or CD1A, is a 322 amino acid single-pass type I membrane protein that localizes to the lumen of the endoplasmic reticulum, as well as to the golgi apparatus, and contains one Ig-like domain. Expressed in a variety of tissues and on cortical thymocytes, dendritic cells and Langerhans cells, CD1E exists as a heterodimer with beta-2-Microglobulin and is necessary for the presentation of glycolipid antigens on the cell surface. CD1E is subject to post-translational mono-ubiquitination and may also be proteolytically cleaved in endosomes to yield a soluble protein. CD1E is present on the surface of some T-cell leukemias, suggesting a possible role in tumorigenesis. Alternative Name :
CD1A; CD1e antigen; CD1E antigen; e polypeptide; CD1e molecule; Swiss-Prot :
P15812 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide CD1e (D248). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9241 CD1e (D248) pAb.
Blocking peptide available as BS9241PP