Product Name :
Tie-1 (F884) Peptide Applications :
Blocking Background :
The cloning and characterization of Tie-1 (also designated Tie), a novel human endothelial cell surface receptor tyrosine kinase, has been reported. The extracellular domain of the predicted Tie-1 protein product has an unusual multi-domain structure consisting of a cluster of three epidermal growth factor homology motifs localized between two immunoglobulin-like loops, which are followed by three Fibronectin type III repeats next to the transmembrane region. An additional member of this family has been identified as Tie-2 (also designated Tek). Tie-1 and Tie-2 have been shown to be encoded by distinct genes and to represent members of a new class of receptor tyrosine kinases. Alternative Name :
Tyrosine-protein kinase receptor Tie-1; TIE1; TIE Swiss-Prot :
P35590 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Tie-1 (F884). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9243 Tie-1 (F884) pAb.
Tie-1 (F884) Peptide Applications :
Blocking Background :
The cloning and characterization of Tie-1 (also designated Tie), a novel human endothelial cell surface receptor tyrosine kinase, has been reported. The extracellular domain of the predicted Tie-1 protein product has an unusual multi-domain structure consisting of a cluster of three epidermal growth factor homology motifs localized between two immunoglobulin-like loops, which are followed by three Fibronectin type III repeats next to the transmembrane region. An additional member of this family has been identified as Tie-2 (also designated Tek). Tie-1 and Tie-2 have been shown to be encoded by distinct genes and to represent members of a new class of receptor tyrosine kinases. Alternative Name :
Tyrosine-protein kinase receptor Tie-1; TIE1; TIE Swiss-Prot :
P35590 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Tie-1 (F884). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9243 Tie-1 (F884) pAb.
Blocking peptide available as BS9243PP