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A Cyclase IX (P974) Peptide BS9246P
Product NameA Cyclase IX (P974) Peptide
Catalog No.BS9246P
ApplicationsBlocking
Swiss-ProtO60503
Product1 mg/ml in DI water.
Purification&PuritySynthetic peptide A Cyclase IX (P974). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage&StabilityStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SpecificityThis peptide can be used with studies using BS9246 A Cyclase IX (P974) pAb.
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1mg $368
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Product Name :
A Cyclase IX (P974) Peptide
Applications :
Blocking
Background :
Classically, adenylyl cyclases respond to receptor-initiated signals, mediated by the Gs and Gi heterotrimeric G proteins. The binding of an agonist to a Gs-coupled receptor (i.e., α β-adrenergic receptor) catalyzes the exchange of GDP (bound to Gα s) for GTP, dissociation of GTP-Gα s from Gbg and Gα s-mediated activation of adenylyl cyclase. The most abundant cerebral adenylyl cyclases appears to be adenylyl cyclase IX. AC IX is confined to the gray matter and its expression is mainly neuronal, with its highest expression located at the hippocampus. ACIX is also expressed in heart, pancreas and thyrocytes. AC I and AC IX are regulated reciprocally by intracellular free Ca2+. The inhibition of AC IX by Ca2+ is blocked by the calcineurin inhibitors FK506 and cyclosporin A.
Alternative Name :
ADCY 9; Adenylate cyclase 9; Adenylate cyclase type 9; Adenylate cyclase type IX; Adenylyl cyclase 9; ATP pyrophosphate lyase 9; KIAA0520; Type IX adenylyl cyclase; Type IX ATP pyrophosphate lyase
Swiss-Prot :
O60503
Product :
1 mg/ml in DI water.
Purification&Purity :
Synthetic peptide A Cyclase IX (P974). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :
This peptide can be used with studies using BS9246 A Cyclase IX (P974) pAb.
Blocking peptide available as BS9246PP
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