Eos (R507) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Eos (R507) Peptide Applications :
Blocking Background :
Members of the Ikaros family contain zinc-finger domains that are involved in DNA-binding and in the formation of homodimers and heterodimers between Ikaros family members. Eos, also known as zinc finger protein Ikaros 4, is a 585 amino acid transcriptional repressor. Localized to the nucleus, Eos may play a role in the development of the central and peripheral nervous systems. Eos self-associates, forms heterodimers with Ikaros family members and interacts with CtBP2, PU.1 and MITF to repress transcription of cathepsin K and TRAP promoters. Eos is expressed at low levels in kidney, thymus, liver and heart, and at high levels in skeletal muscle. Alternative Name :
EOS; Eos protein; IKAROS family zinc finger 4 (Eos); IKAROS family zinc finger 4; Ikaros family zinc finger protein 4; IKZF4; ZNFN1A4; Swiss-Prot :
Q9H2S9 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Eos (R507). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9253 Eos (R507) pAb.
Eos (R507) Peptide Applications :
Blocking Background :
Members of the Ikaros family contain zinc-finger domains that are involved in DNA-binding and in the formation of homodimers and heterodimers between Ikaros family members. Eos, also known as zinc finger protein Ikaros 4, is a 585 amino acid transcriptional repressor. Localized to the nucleus, Eos may play a role in the development of the central and peripheral nervous systems. Eos self-associates, forms heterodimers with Ikaros family members and interacts with CtBP2, PU.1 and MITF to repress transcription of cathepsin K and TRAP promoters. Eos is expressed at low levels in kidney, thymus, liver and heart, and at high levels in skeletal muscle. Alternative Name :
EOS; Eos protein; IKAROS family zinc finger 4 (Eos); IKAROS family zinc finger 4; Ikaros family zinc finger protein 4; IKZF4; ZNFN1A4; Swiss-Prot :
Q9H2S9 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Eos (R507). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9253 Eos (R507) pAb.
Blocking peptide available as BS9253PP