JIK (H571) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
JIK (H571) Peptide Applications :
Blocking Background :
JNK/SAPK-inhibitory kinase (JIK) is a serine/threonine kinase that belongs to the STE20 kinase family. The kinase domain of JIK is similar to the GCK-like subfamily of STE20 kinases, while its non-catalytic domain is similar to a Caenorhabditis elegans putative serine/threonine kinase, SULU. JIK inhibits c-Jun NH2-terminal kinase/stress-activated protein kinase (JNK/SAPK), which is activated by many types of cellular stresses and extracellular signals. JNK/SAPK regulates cell survival, apoptosis and proliferation in mouse development. JIK is negatively regulated by epidermal growth factor (EGF) and tyrosine kinase receptors. In unstimulated human T cells, JIK is cytoplasmic, whereas in the continuously dividing human T cells of Jurkat lymphoma, JIK is nuclear. Alternative Name :
KDS; MAP3K18; TAO kinase 3; TAOK3; DPK; FLJ31808; hKFC A; hKFC-A; Swiss-Prot :
Q9H2K8 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide JIK (H571). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9257 JIK (H571) pAb.
JIK (H571) Peptide Applications :
Blocking Background :
JNK/SAPK-inhibitory kinase (JIK) is a serine/threonine kinase that belongs to the STE20 kinase family. The kinase domain of JIK is similar to the GCK-like subfamily of STE20 kinases, while its non-catalytic domain is similar to a Caenorhabditis elegans putative serine/threonine kinase, SULU. JIK inhibits c-Jun NH2-terminal kinase/stress-activated protein kinase (JNK/SAPK), which is activated by many types of cellular stresses and extracellular signals. JNK/SAPK regulates cell survival, apoptosis and proliferation in mouse development. JIK is negatively regulated by epidermal growth factor (EGF) and tyrosine kinase receptors. In unstimulated human T cells, JIK is cytoplasmic, whereas in the continuously dividing human T cells of Jurkat lymphoma, JIK is nuclear. Alternative Name :
KDS; MAP3K18; TAO kinase 3; TAOK3; DPK; FLJ31808; hKFC A; hKFC-A; Swiss-Prot :
Q9H2K8 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide JIK (H571). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9257 JIK (H571) pAb.
Blocking peptide available as BS9257PP