IL-11Rα (D361) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
IL-11Rα (D361) Peptide Applications :
Blocking Background :
The pleiotropic cytokine, IL-11, has been shown to have proliferative and differentiation effects on lymphopoietic, myeloid and erythroid cells. IL-11 also has the inhibiting effect of repressing adipogenesis in vitro. The IL-11α receptor, IL-11Rα, is a member of the class 1 subgroup of the cytokine receptor family and exhibits structural similarity to the α subunits of the human ciliary neurotrophic factor (CNTF) and the mouse IL-6 receptor. It is speculated that the IL-11Rα regulates the proliferation and/or differentiation of skeletogenic progenitor and mesenchymal cells. Coexpression of gp130 and IL-11α is necessary for high-affinity binding of IL-11 to IL-11Rα. It has also been found that coexpression of IL-11Rα and gp130 is required for proper stimulation of Ba/F3 cells to differentiate into macrophage in response to IL-11. Alternative Name :
CRSDA; hCG_2011440; I11RA; IL-11 receptor subunit alpha; IL-11R subunit alpha; IL-11R-alpha; IL-11RA; IL11RA; Interleukin 11 receptor alpha; Interleukin 11 receptor alpha chain; Interleukin-11 receptor subunit alpha; MGC2146; Swiss-Prot :
Q14626 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide IL-11Rα (D361). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9265 IL-11Rα (D361) pAb.
IL-11Rα (D361) Peptide Applications :
Blocking Background :
The pleiotropic cytokine, IL-11, has been shown to have proliferative and differentiation effects on lymphopoietic, myeloid and erythroid cells. IL-11 also has the inhibiting effect of repressing adipogenesis in vitro. The IL-11α receptor, IL-11Rα, is a member of the class 1 subgroup of the cytokine receptor family and exhibits structural similarity to the α subunits of the human ciliary neurotrophic factor (CNTF) and the mouse IL-6 receptor. It is speculated that the IL-11Rα regulates the proliferation and/or differentiation of skeletogenic progenitor and mesenchymal cells. Coexpression of gp130 and IL-11α is necessary for high-affinity binding of IL-11 to IL-11Rα. It has also been found that coexpression of IL-11Rα and gp130 is required for proper stimulation of Ba/F3 cells to differentiate into macrophage in response to IL-11. Alternative Name :
CRSDA; hCG_2011440; I11RA; IL-11 receptor subunit alpha; IL-11R subunit alpha; IL-11R-alpha; IL-11RA; IL11RA; Interleukin 11 receptor alpha; Interleukin 11 receptor alpha chain; Interleukin-11 receptor subunit alpha; MGC2146; Swiss-Prot :
Q14626 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide IL-11Rα (D361). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9265 IL-11Rα (D361) pAb.
Blocking peptide available as BS9265PP